ישראל מירסקי

אקדמי בכיר

Back-in-Time Diffusion

Unsupervised Detection of Medical Deepfakes

Fred M. Grabovski, Lior Yasur, Guy Amit, Yisroel Mirsky

Recent progress in generative models has made it easier for a wide audience to edit and create image content, raising concerns about the proliferation of deepfakes, especially in healthcare. Despite the availability of numerous techniques for detecting manipulated images captured by conventional cameras, their applicability to medical images is limited. This limitation stems from the distinctive forensic characteristics of medical images, a result of their imaging process. In this work, we propose a novel anomaly detector for medical imagery based on diffusion models. Normally, diffusion models are used to generate images. However, we show how a similar process can be used to detect synthetic content by making a model reverse the diffusion on a suspected image. We evaluate our method on the task of detecting fake tumors injected and removed from CT and MRI scans. Our method significantly outperforms other state-of-the-art unsupervised detectors with an increased AUC of 0.9 from 0.79 for injection and of 0.96 from 0.91 for removal on average. We also explore our hypothesis using AI explainability tools and publish both our code and new medical deepfake datasets to encourage further research into this domain.

שפת פרסום אנגלית
כתב עת ACM Transactions on Intelligent Systems and Technology
כרך 16
נושא מספר 6
סטטוס פרסום פורסם - 17.10.2025
מספר מאמר 123

Keywords

CT scans
MRI
anomaly detection
diffusion models
medical deepfakes
unsupervised learning

ASJC Scopus subject areas

Theoretical Computer Science
Artificial Intelligence
גישה למסמך
10.1145/3744656
קבצים וקישורים אחרים
Link to publication in Scopus