Dan Levy

The overall research goal in the lab is based on the hypothesis that dynamic
methylation of histone and non-histone proteins plays an important role
in epigenetic regulation of cellular signal transduction pathways with a
fundamental effect on human health. We utilize interdisciplinary biochemical
and cellular approaches and cutting-edge genomic and proteomic tools to
decipher the molecular mechanisms by which lysine methylation through
epigenetics programs regulates oncogenic and cell differentiation processes.
We aim to identify new methylation events on histone and non-histone
proteins; define the molecular mechanisms by which these methyl marks are
generated and transduced; unravel the clinical relevance of these events and
translate this knowledge to develop therapeutic applications in the future.

Laboratory location: NIBN, Building 41, 1st floor, room 104.

Contact: ledan@post.bgu.ac.il

Personal Site: http://lifeserv.bgu.ac.il/wp/ledan/