
David Stepensky
Pharmacokinetics, pharmacodynamics, and drug delivery systems
Our lab investigates the processes that govern drug transport in the body and their pharmacological effects. Each drug has a unique set of biopharmaceutical, pharmacokinetic, and pharmacodynamic properties that vary between individual patients and frequently necessitate dose and treatment adjustments. We analyze the dose-concentration-effect relationships of drugs in laboratory animals and patients and use mathematical/statistical analysis (PK-PD modeling) to quantitatively describe these relationships. An in-depth understanding of the processes of drug transport and pharmacological effects serves as a basis for the design, development, and characterization of drug delivery systems for targeting drugs to their site of action and enhancing their efficacy/safety balance in the individual patients.
Email: davidst@bgu.ac.il
Phone: 054-5349669
Orcid ID: 0000-0001-7206-8352
Personal website: https://fohs.bgu.ac.il/research/profileBrief.aspx?id=VurisurMt
