Department of Clinical Biochemistry and Pharmacology
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David Ben-Menahem

Molecular endocrinology

The research focuses on key hormones in human reproduction, mainly the gonadotropins LH, hCG, and FSH, using a humanized Drosophila model developed in collaboration with Dr. Ross Cagan (formerly at Mount Sinai Medical School, New York). Open research projects in the lab include 1. The use of the humanized Drosophila model for exploring the mechanism of gonadotropin receptor action in a calorie-rich diet and insulin resistance. 2. Elucidating potential non-classical gonadotropin activities outside the gonads. 3. Development of a Drosophila platform for an accelerated search of orally bioactive gonadotropin receptor agonists and antagonists.

Email: dbm@bgu.ac.il