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Yifat Miller

Senior Academic

Termini capping of metal-poly-His peptide complexes induces the formation of α-helix

Eyal Simonovsky, Henryk Kozlowski, Yifat Miller

An ensemble of structures of metal-hexa-histidine-tag capped and uncapped peptides has been studied using molecular dynamics simulations. The metal-binding peptides are polymorphic for both capped and uncapped peptides. The capping of the peptide termini promotes α-helical conformations that are induced by the metal binding sites.

Publication language English
Pages 104551-104555
Journal RSC Advances
Volume 5
Issue number 126
Publication status Published - 01.12.2015

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering
Access to Document
10.1039/c5ra15385a
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Link to publication in Scopus