Weizmann Group
Synthetic nucleic acids and photothermal nanomaterials design group
Magnetically amplified DNA assays (MADA)
Sensing of viral DNA and single-base mis-matches by using nucleic acid modified magnetic particles
Taking DNA analysis for a spin: Amplified detection of viral DNA and single-base mutations in nucleic acids is accomplished by the thermally cycled incorporation of biotin labels into DNA replica associated with magnetic particles, by the electrocatalyzed biochemiluminescence transduction of the DNA recognition events, and by the rotation of the magnetic particles on electrode surfaces (see schematic representation).
| Publication language | English |
| Pages | 2372-2376 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 42 |
| Issue number | 21 |
| Publication status | Published - 30.05.2003 |
Keywords
Biosensors
Chemiluminescence
DNA
Magnetic particles
ASJC Scopus subject areas
Catalysis
General Chemistry
