Prof. Michal Ziv-Yukelson

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On the Common Substring Alignment Problem

Gad M. Landau, Michal Ziv-Ukelson

The Common Substring Alignment Problem is defined as follows: Given a set of one or more strings S1, S2 . . . Sc and a target string T, Y is a common substring of all strings Si, that is, Si = BiYFi. The goal is to compute the similarity of all strings Si with T, without computing the part of Y again and again. Using the classical dynamic programming tables, each appearance of Y in a source string would require the computation of all the values in a dynamic programming table of size O(nℓ) where ℓ is the size of Y. Here we describe an algorithm which is composed of an encoding stage and an alignment stage. During the first stage, a data structure is constructed which encodes the comparison of Y with T. Then, during the alignment stage, for each comparison of a source Si with T, the precompiled data structure is used to speed up the part of Y. We show how to reduce the O(nℓ) alignment work, for each appearance of the common substring Y in a source string, to O(n)-at the cost of O(nℓ) encoding work, which is executed only once.

Publication language English
Pages 338-359
Journal Journal of Algorithms
Volume 41
Issue number 2
Publication status Published - 01.01.2001

Keywords

Candidate lists
Design and analysis of algorithms
Dynamic programming
Monge arrays
Repeated substrings
Sequence comparison
Shared substrings

ASJC Scopus subject areas

Control and Optimization
Computational Mathematics
Computational Theory and Mathematics
Access to Document
10.1006/jagm.2001.1191
Other files and links
Link to publication in Scopus