Laboratory for Systems Chemistry

Prof. Gonen Ashkenasy Research Group

Novel NO biosensor based on the surface derivatization of GaAs by "hinged" iron porphyrins

Deng Guo Wu, Gonen Ashkenasy, Dmitry Shvarts, Rachel V. Ussyshkin, Ron Naaman, Abraham Shanzer, David Cahen

A tailor-made, two-component molecular system bound to a GaAs based electronic device has been used to detect nitric oxide (NO) in physiological buffer solutions down to a concentration of 1 ppm (ca. 3 μM). This is made possible because the current through the GaAs changes when NO binds to an iron(III) porphyrin (see picture).

Publication language English
Pages 4496-4500
Volume 39
Issue number 24
Publication status Published - 15.12.2000

Keywords

Biosensors
Nitrogen oxides
Porphyrinoids
Surface chemistry

ASJC Scopus subject areas

Catalysis
General Chemistry