Danny Barash

Senior Academic

Modeling-Based Response-Guided DAA Therapy for Chronic Hepatitis C to Identify Individuals for Shortening Treatment Duration

Ashish Goyal, Alex Churkin, Danny Barash, Scott J. Cotler, Amir Shlomai, Ohad Etzion, Harel Dahari

Shortening duration of direct-acting antiviral therapy for chronic hepatitis C could provide cost savings, reduce medication exposure, and foster adherence and treatment completion in special populations. The current analysis indicates that measuring hepatitis C virus at baseline and on days 7 and 14 of therapy can identify patients for shortening therapy duration.

Publication language English
Journal Open Forum Infectious Diseases
Volume 9
Issue number 5
Publication status Published - 01.05.2022
ofac157

Keywords

Direct-acting antivirals
Hepatitis C virus
Mathematical modeling
Response-guided therapy
Time to cure

ASJC Scopus subject areas

Oncology
Infectious Diseases

Sustainable Development Goals

SDG 3 - Good Health and Well-being
Access to Document
10.1093/ofid/ofac157
Other files and links
Link to publication in Scopus