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Designing RNA switches for synthetic biology using inverse-RNA-folding

Sumit Mukherjee, Danny Barash

RNA switches respond to specific ligands to control gene expression. They are widely used in synthetic biology applications and hold potential for future RNA-based therapeutic breakthroughs. However, the crux is their precise design. Here, we will discuss how inverse-RNA-folding could be utilized for the accurate design of RNA switches.

שפת פרסום אנגלית
דפים 517-521
כתב עת Trends in Biotechnology
כרך 42
נושא מספר 5
סטטוס פרסום פורסם - 01.05.2024

Keywords

RNA switch
RNA-based therapeutics
inverse-RNA-folding
riboswitch
ribozyme
synthetic biology

ASJC Scopus subject areas

Biotechnology
Bioengineering
קבצים וקישורים אחרים
Link to publication in Scopus