Prof. Dan Barash
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Designing RNA switches for synthetic biology using inverse-RNA-folding
RNA switches respond to specific ligands to control gene expression. They are widely used in synthetic biology applications and hold potential for future RNA-based therapeutic breakthroughs. However, the crux is their precise design. Here, we will discuss how inverse-RNA-folding could be utilized for the accurate design of RNA switches.
| Publication language | English |
| Pages | 517-521 |
| Journal | Trends in Biotechnology |
| Volume | 42 |
| Issue number | 5 |
| Publication status | Published - 01.05.2024 |
Keywords
RNA switch
RNA-based therapeutics
inverse-RNA-folding
riboswitch
ribozyme
synthetic biology
ASJC Scopus subject areas
Biotechnology
Bioengineering
