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Profile picture of Prof. Elie Beit - Yannai

Prof. Elie Beit - Yannai

Recruiting Graduate Students

Departments

  • Associate Professor

    חבר/ת סגל אקדמי בכיר

    Faculty of Health Sciences, Department of Clinical Biochemistry and Pharmacology

    M6 - Ruth & Heinz Horst Deichmann Sciences Building Floor 5 Room 533, Soroka Health Sciences

    08-647-7352

Staff member contact section

bye@bgu.ac.il

About

I am an Associate Professor at Ben-Gurion University of the Negev, where I have been a faculty member since 2004. I am a pharmacist by training, having earned my B.Pharm from the School of Pharmacy at the Hebrew University of Jerusalem, followed by a Master?s degree in Medicinal Chemistry and a PhD ןמ Pישרצשבםךםעט from the same institution. Industrial Expertise & Leadership Prior to my academic appointment at BGU, I spent five years in the biotech industry, where I served as a research scientist . This experience provided me with a deep understanding of translational research and the operational complexities of pharmaceutical development, which I now apply to my leadership of academic research teams and the mentorship of graduate students. Research Interests: The Pharmacology of the Eye My research program explores the molecular pharmacology of intraocular tissues, with a specific focus on primary open-angle glaucoma (POAG). I am interested in how cells communicate to maintain ocular homeostasis and how this communication breaks down in disease states. Extracellular Vesicles (EVs) & Exosome Signaling: I study the role of exosomes as messengers between the non-pigmented ciliary epithelium (NPCE) and the trabecular meshwork (TM). This "crosstalk" is vital for regulating intraocular pressure. Wnt Pathway & ECM Remodeling: My work characterizes how exosomal cargo modulates the Wnt signaling pathway and influences Extracellular Matrix (ECM) remodeling, particularly collagen formation in the ocular drainage system. Oxidative Stress & Neuroprotection: I investigate how oxidative stress impacts ocular neurodegeneration and the capacity of exosomes to carry anti-oxidative signals to protect drainage cells. Molecular Profiling: Using advanced microarray and genomic analysis, I profile exosomal microRNA (miRNA) to identify key gene targets relevant to glaucoma pathology.

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