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Adi Weintraub

Senior Academic

Maternal and fetal outcomes among women with GDMA1 before and post-date

Eyal Weiss, Tamar Eshkoli,Yael Baumfeld, Reut Rotem, Gurkamaljot Kaur, Adi Y. Weintraub

Objective: To investigate adverse pregnancy outcomes in patients complicated with GDMA1 who delivered at term before or after 40 weeks of gestation. Study Design: A population-based cohort study including all women with GDMA1 during pregnancy was conducted. Deliveries occurred between 1988 and 2016 at a large university tertiary medical center. Results: During the study period, 11,765 women with GDMA1 met the inclusion criteria. Of these, 1303 (11 %) delivered after 40 weeks (post-date, study group), while 10,462 (89 %) delivered at term before 40 weeks of gestation (before date, control group). Those who delivered after 40 weeks of gestation (the study group) had a significantly lower percent of cesarean deliveries (CD), higher rates of spontaneous vaginal deliveries and induction of labor in comparison to those who delivered before 40 weeks of gestation (the control group). The control group had significantly higher rates of preeclampsia and intrauterine growth restriction than the study group. Using a multivariable logistic regression model, delivery after 40 weeks was noted as an independent protective factor for CD (adjusted OR = 0.78, 95 %CI 0.66–0.92, p value = 0.001). Delivery after 41 + 0 weeks had a significantly higher rate of CD and LGA. Conclusion: No significant increase in adverse pregnancy outcomes at term post-date pregnancies complicated with GDMA1 was demonstrated. Furthermore, there was no increase in the rate of CD with the increase in gestational age until 41 weeks of gestation.

Publication language English
Pages 44-49
Journal European Journal of Obstetrics, Gynecology and Reproductive Biology
Volume 293
Publication status Published - 01.02.2024

Keywords

GDMA1
Gestational age
Gestational diabetes mellitus
Macrosomia
Term pregnancy

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

Sustainable Development Goals

SDG 3 - Good Health and Well-being