Tal Shay

Senior Academic

Our research

Comparative Transcriptomics of the Immune System

Our group studies the immune system using computational methods. We want to understand what changes in immune cells during differentiation and activation, and how immune cells interact with each other and with the environment.

Current research projects:

(1) Splicing changes in the immune system.

(2) Evolutionary conservation and divergence of the immune system transcriptome.

(3) The immune component of long COVID.

Our lab is a member of the Immunological Genome consortium (ImmGen) and the NeuroCOV consortia.

More about the research

Latest publications

2026
Gestational Diabetes Mellitus Alters Placental Precursor mRNA Splicing.

2024
Comparison and development of cross-study normalization methods for inter-species transcriptional analysis.

More Publications

Group members

Team page

Prof. Tal Shay

Principal Investigator

Dr. Hadas Ner-Gaon

Lab manager

Dr. Stav Biton

Postdoctoral fellow

Tal Ben-Tovim

M.Sc. student

Sharon Glazer

M.Sc. student

Ben-Gurion University of the Negev to honor Katharina von Schnurbein

10/04/2024

Katharina von Schnurbein, European Commission Coordinator on combating antisemitism and fostering Jewish life, will be awarded an honorary doctorate at the upcoming Board of Governors Meeting to be held in May.

To Read the Article

BGU researchers discover improved ionization method to detect molecular oxygen

07/04/2024

A new laser spectroscopy scheme for molecular oxygen achieves roughly two orders of magnitude higher sensitivity for fully rotationally resolved spectra than the previous state of the art

To Read the Article

A targeted polymer to treat colorectal cancer liver metastases

07/04/2024

A nanosized polymer, developed by a research team from Ben-Gurion University of the Negev, can selectively deliver chemotherapeutic drugs to blood vessels that feed tumors and metastases, and has emerged as an effective treatment for advanced cancer

To Read the Article

Lightning and Thunder

01/04/2024

The IDF and Ben-Gurion University of the Negev open two new elite academic programs for future recruits

To Read the Article

Funding

Join us

We are looking for excellent M.Sc. and Ph.D. students to take part in a study of the immune system using bioinformatics tools. The lab focuses on identifying the transcriptional changes of the immune system and their regulation during interactions with pathogens, microbiome, cancer and auto-immune diseases. The lab is a multidisciplinary environment; we need both people with strong computational skills and analytic abilities and people with profound immunological understanding. The successful candidate should be curious, hardworking, fast learner, and have one of the following: 1) A B.Sc. or M.Sc. in computer science, engineering or related disciplines, and a deep interest in biological processes. 2) A B.Sc. or M.Sc. in biology and the will to learn and conduct computational research. Project students The laboratory is also looking for enthusiastic and talented students to take part in the study of the immune system using bioinformatics tools. Projects require programming. To hear more, please write to Tal Shay. Informal inquiries are welcome.