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Michael M. Meijler

   Professor, Department of Chemistry and National Institute for Biotechnology in the Negev,
   Ben-Gurion University of the Negev, Be'er-Sheva, Israel
   

 

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Publications


76. A. Gupta, L. Holoidovsky, C. Thamaraiselvan, A. K. Thakur, S. P. Singh, M. M. Meijler, C. J. Arnusch: Silver-doped laser-induced graphene for potent surface antibacterial activity and anti-biofilm action Chem. Commun., 55(48), 6890-93 (2019) PDF

75. O. Gorelik, N. Levy, L. Shaulov, K. Yegodayev, M. M. Meijler, N. Sal-Man: Vibrio cholerae autoinducer-1 enhances the virulence of enteropathogenic Escherichia coli Sci. Rep., 9, 4122 (2019) PDF

74. H. Ganin, N. Kemper, S. Meir, I. Rogachev, S. Ely, H. Massalha, A. Mandabi, A. Keren-Paz, A. Shanzer, M. M. Meijler, S. Malitsky, A. Aharoni, I. Kolodkin-Gal: Photo-switchable microbial fuel-cells Biotechnol. Bioengin., in press (2018) PDF

73. R. Malishev, E. Tayeb-Fligelman, S. David, M. M. Meijler, M. Landau, R. Jelinek: Reciprocal Interactions between Membrane Bilayers and S. aureus PSM alpha 3 Cross-alpha Amyloid Fibrils Account for Species-Specific Cytotoxicity J. Mol. Biol., 430(10), 1431-1441 (2018) PDF

72. O. Schlesinger, M. Pasi, R. Dandela, M. M. Meijler, L. Alfonta: Electron transfer rate analysis of a site-specifically wired copper oxidase Phys. Chem. Chem. Phys. , 20(9), 6159-6166 (2018) PDF

71. O. Schlesinger, R. Dandela, A. Bhagat, M. M. Meijler, L. Xia, L. Alfonta: Photo-switchable microbial fuel-cells Biotechnol. Bioengin., 115(5), 1355-1360 (2018) PDF

70. R. Dandela, D. Mantin, B. F. Cravatt, J. Rayo, M. M. Meijler: Proteome-wide mapping of PQS-interacting proteins in Pseudomonas aeruginosa Chem. Sci., 9(8), 2290-2294 (2018) PDF

69. R. Gregor, S. David, M. M. Meijler: Chemical strategies to unravel bacterial-eukaryotic signaling Chem. Soc. Rev., 47(5), 1761-1772 (2018) PDF

68. S. David, A. Mandabi, S. Uzi, A. Aharoni, M. M. Meijler: Mining plants for bacterial quorum sensing modulators ACS Chem. Biol., 13(1), 247-252 (2018) PDF

67. N. Nandakumar, R. Dandela, J. Gopas, M. M. Meijler: Quorum sensing modulators exhibit cytotoxicity in Hodgkin's lymphoma cells and interfere with NF-kappa B signaling Bioorg. Med. Chem. Lett., 27(13), 2967-2973 (2017) PDF

66. Y. Elharar, S. Schlussel, N. Hecht, M. M. Meijler, E. Gur: The regulatory significance of tag recycling in the mycobacterial Pup-proteasome system FEBS J., 284(12), 1804-1814 (2017) PDF

65. R. Dandela, R. Mashiach, R. Adepu, R. Gregor, M. Athamna, E. Zecharia, O. Ernst, T. Zor, M. M. Meijler: Synthesis and evaluation of a tag-free photoactive phospho-ceramide analogue-1 (PCERA-1) probe to study immunomodulation in macrophages Chem. Commun., 53(27), 3842-3845 (2017) PDF

64. M. Ritenberg, S. Nandi, S. Kolusheva, R. Dandela, M. M. Meijler, R. Jelinek: Imaging Pseudomonas aeruginosa Biofilm Extracellular Polymer Scaffolds with Amphiphilic Carbon Dots ACS Chem. Biol., 11(5), 1265-1270 (2016) PDF

Editorial: M. M. Meijler: Understanding the Collective Nose of Bacteria Cell Chem. Biol., 23(3), 317-318 (2016) PDF

63. S. Katz, O. Ernst, D. Avni, M. Athamna, A. Philosoph, L. Arana, A. Ouro, L. A. Hoeferlin, M. M. Meijler, C. E. Chalfant, A. Gomez-Munoz, T. Zor: Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors Imunnol. Lett. , 169, 73-81 (2016) PDF

62. N. Amara, R. Gregor, J. Rayo, R. Dandela, E. Daniel, N. Liubin, H. M. E. Willems, A. Ben-Zvi, B. P. Krom, M. M. Meijler: Fine-Tuning Covalent Inhibition of Bacterial Quorum Sensing ChemBioChem, 17(9), 825-835 (2016) PDF

61. B. P. Krom, N. Levy, M. M. Meijler, M. A. Jabra-Rizk: Farnesol and Candida albicans: Quorum Sensing or Not Quorum Sensing? Isr. J. Chem., 56(5), 295-301 (2016) PDF

Editorial: M. M. Meijler: Quorum Sensing and Chemical Communication Between Species Isr. J. Chem., 56(5), 264 (2016) PDF

60. A. Delago, A. Mandabi, M. M. Meijler: Natural Quorum Sensing Inhibitors – Small Molecules, Big Messages Isr. J. Chem., 56(5), 310-320 (2016) PDF

59. A. Mandabi, H. Ganin, M. M. Meijler: Synergistic Activation of Quorum Sensing in Vibrio harveyi Bioorg. Med. Chem. Lett., 25(18), 3966-3969 (2015) PDF

Editorial: M. Köhn, M. M. Meijler, M. Kaiser: Building Up a Chemical Proteomics Network in Europe and Beyond ACS Chem. Biol., 9, 1647–1648 (2014) PDF

58. E. W. Bachtiar, B. M. Bachtiar, L. M. Jarosz, L. Amir, H. Sunarto, H. Ganin, M. M. Meijler, B. P. Krom: AI-2 of Aggregatibacter actinomycetemcomitans Inhibits Candida albicans Biofilm Formation Frontiers Cell. Inf. Microbiol., 4, 94 (2014) PDF

57. A. Mandabi, H. Ganin, J. Rayo, M. M. Meijler: Karrikins from Plant Smoke Modulate Bacterial Quorum Sensing Chem. Commun., 50, 5322-5325 (2014) PDF

56. A. Achiron, R. Mashiach, R. Zilkha-Falb, M. M. Meijler, M. Gurevich: Polymerase I Pathway Inhibitor Ameliorates Experimental Autoimmune Encephalomyelitis J. Neuroimmunol., 263, 91-97 (2013) PDF

55. N. Rabin, A. Delago, B. Inbal, P. Krief, M. M. Meijler: Tailor Made LasR Agonists Modulate Quorum Sensing in Pseudomonas aeruginosa Org. Biomol. Chem., 11, 7155-7163 (2013) PDF

54. L. Dubinsky, A. Delago, N. Amara, P. Krief, J. Rayo, T. Zor, V. V. Kravchenko, M. M. Meijler: Species selective diazirine positioning in tag-free photoactive quorum sensing probes Chem. Commun., 49, 5826-5828 (2013) PDF

53. Y. Glucksam-Galnoy, R. Sananes, N. Silberstein, P. Krief, V. V. Kravchenko, M. M. Meijler, T. Zor: The bacterial quorum-sensing signal molecule N-3-oxo-dodecanoyl-L-homoserine lactone reciprocally modulates pro- and anti-inflammatory cytokines in activated macrophages J. Immunol., 191 (1), 337-44 (2013) PDF

52. S. Melamed Yerushalmi, N. G. Lemcoff, M. M. Meijler: Multivalent alteration of quorum sensing in Staphylococcus aureus Chem. Commun., 49, 5177-5179 (2013) PDF

51. R. Mashiach, M. M. Meijler: Total synthesis of pyoverdin D Org. Lett., 15(7), 1702-1705 (2013) PDF

50. L. Amir, S. Carnally, J. Rayo, S. Rosenne, S. Melamed Yerushalmi, O. Schlesinger, M. M. Meijler, L. Alfonta: Surface display of a redox enzyme and its site specific wiring to gold electrodes J. Am. Chem. Soc., 135, 70-73 (2013) PDF

49. H. Ganin, J. Rayo, N. Amara, N. Levy, P. Krief, M. M. Meijler: Sulforaphane and erucin, natural isothiocyanates from broccoli, inhibit bacterial quorum sensing MedChemComm, 4, 175-179 (2013) PDF

48. J. Monfregola, J. L. Johnson, M. M. Meijler, G. Napolitano, S. D. Catz: Munc13-4 regulates the oxidative response and is essential for phagosomal maturation and bacterial killing in neutrophils J. Biol. Chem., 287(53), 44603-44618 (2012) PDF

47. N. Ofer, M. Wishkautzan, M. M. Meijler, Y. Wang, A. Speer, M. Niederweis, E. Gur: Ectoine biosynthesis in Mycobacterium smegmatis Appl. Environ. Biol., 78(20, 7483–7486 (2012) PDF

46. M. Ritenberg, S. Kolusheva, H. Ganin, M. M. Meijler, R. Jelinek: Biofilm formation on chromatic sol–gel/polydiacetylene films ChemPlusChem, 77(9), 752-757 (2012) PDF

45. H. Ganin, Y. Danin-Poleg, Y. Kashi, M. M. Meijler: Vibrio cholerae Autoinducer CAI-1 interferes with Pseudomonas aeruginosa quorum sensing and inhibits its growth ACS Chem. Biol., 7, 659-665, (2012) PDF

44. D. Amar, I. Berger, N. Amara, G. Tafa, M. M. Meijler, A. Aharoni: The transition of human estrogen dulfotransferase from generalist to specialist using directed enzyme evolution J. Mol. Biol., 416(1), 21-32, (2012) PDF

43. L. Dubinsky, B. P. Krom, M. M. Meijler: Diazirine Based Photoaffinity Labeling Bioorg. Med. Chem., 20(2), 554-570, (2012) PDF

42. L. M. Jarosz, E. S. Ovchinnikova, M. M. Meijler, B. P. Krom: Microbial Spy Games and Host Response; roles of a Pseudomonas aeruginosa small molecule in communication with other species PLOS Pathogens, 7(11), e1002312, (2011) PDF

41. J. Rayo, N. Amara, P. Krief, M. M. Meijler: Live cell labeling of native intracellular bacterial receptors using aniline-catalyzed oxime ligation J. Am. Chem. Soc., 133(19), 7469-75, (2011) PDF

40. M. Goldsmith, A. Daka, N. F. Lamour, R. Mashiach, Y. Glucksam, M. M. Meijler, C. E. Chalfant, T. Zor: A ceramide analog inhibits cPLA2 activity and consequent PGE2 formation in LPS-stimulated macrophages Immunol. Lett., 135, 136-143 (2011) PDF

39. N. Amara, B. P. Krom, G. F. Kaufmann, M. M. Meijler: Macromolecular Inhibition of Quorum Sensing: Enzymes, Antibodies and Beyond Chem. Rev.,111(1), 195-208, (2011) PDF

38. D. Avni, A. Philosoph, M. M. Meijler, T. Zor: The ceramide-1-phosphate analog PCERA-1 modulates TNFa and IL-10 production in macrophages via the cAMP-PKA-CREB pathway in a GTP-dependent manner Immunology,129(3), 375-385 (2010) PDF

37. M. Levi, M. M. Meijler, A. Gómez-Muñoz, T. Zor: Distinct receptor-mediated activities in macrophages for natural ceramide-1-phosphate (C1P) and for phospho-ceramide analogue-1 (PCERA-1) Mol. Cell. Endocrinol., 314(2), 248-255, (2010) PDF

36. L. Dubinsky, L. M. Jarosz, N. Amara, P. Krief, V. Kravchenko, B. P. Krom, M. M. Meijler: Synthesis and validation of a probe to identify quorum sensing receptors Chem. Commun., 47, 7378-80, (2009)

35. C. A. Lowery, J. Park, C. Gloeckner, M. M. Meijler, R. S. Mueller, H. I. Boshoff, R. L. Ulrich, C. E. Barry, III, D. H. Bartlett, V. V. Kravchenko, G. F. Kaufmann, K. D. Janda: Defining the Mode of Action of Tetramic Acid Antibacterials Derived from Pseudomonas aeruginosa Quorum Sensing Signals J. Am. Chem. Soc.,131(40), 14473-9, (2009) PDF

34. N. Amara, R. Mashiach, D. Amara, P. Krief, S. A. Spieser, M. J. Bottomley, A. Aharoni, M. M. Meijler: Covalent Inhibition of Bacterial Quorum Sensing J. Am. Chem. Soc., 131(30), 10610-10619, (2009) PDF

33. H. Ganin, X. Tang, M. M. Meijler: Inhibition of Pseudomonas aeruginosa Quorum Sensing by AI-2 analogs Bioorg. Med. Chem. Lett., 19 (14), 3941-3944,(2009) PDF

32. M. Goldsmith, D. Avni, O. Ernst, Y. Glucksam, G. Levy-Rimler, M. M. Meijler, T. Zor: Synergistic IL-10 Induction by LPS and the Ceramide-1-phosphate Analog PCERA-1 is Mediated by the cAMP and p38 MAP Kinase Pathways Mol. Immunol., 46(10), 1979-87, (2009) PDF

31. O. Bukelman, N. Amara, R. Mashiach, P. Krief, M. M. Meijler, L. Alfonta: Electrochemical Analysis of Quorum Sensing Inhibition Chem. Commun., 2836-2838, (2009) PDF

30. D. Avni, M. Goldsmith, O. Ernst, R. Mashiach, T. Tuntland, M. M. Meijler, N. S. Gray, H. Rosen, T. Zor: Modulation of TNFalpha, IL-10 and IL-12p40 Levels by a Ceramide-1-phosphate analog, PCERA-1, in vivo and ex vivo in Primary Macrophages Immunol. Lett., 123, 1-8, (2009) PDF

29. L. Amir, T. K. Tam, M. Pita, M. M. Meijler, L. Alfonta, E. Katz: Biofuel Cell Controlled by Enzyme Logic Systems J. Am. Chem. Soc., 131(2), 826-32, (2009) PDF

28. M. Goldsmith, D. Avni, G. Levy-Rimler, R. Mashiach, O. Ernst, M. Levi, B. Webb, M. M. Meijler, N. S. Gray, H. Rosen, T. Zor: A Ceramide-1-phosphate Analogue, PCERA-1, Simultaneously Suppresses Tumour Necrosis Factor-alpha and Induces Interleukin-10 Production in Activated Macrophages. Immunology, 127(1), 103-15, (2009) PDF

27. A. V. Mayorov, N. Amara, J. Y. Chang, J. A. Moss, M. S. Hixon, D. I. Ruiz, M. M. Meijler, E. P. Zorrilla, K. D. Janda: Catalytic Antibody Degradation of Ghrelin Increases Whole-body Metabolic Rate and Reduces Refeeding in Fasting Mice Proc. Natl. Acad. Sci. USA , 105(45), 17487-92, (2008) PDF

26. V. V. Kravchenko, G. F. Kaufmann, J. C. Mathison, D. A. Scott, A. Z. Katz, D. C. Grauer, M. Lehmann, M. M. Meijler, K. D. Janda, R. J. Ulevitch: Modulation of Gene Expression via Disruption of NF-{kappa}B Signaling by a Bacterial Small Molecule. Science, 319 (5867), 1232-5, (2008) PDF

25. E. W. Debler, G. F. Kaufmann, M. M. Meijler, A. Heine, J. M. Mee, G. Pjlevaljcic, A. J. Di Bilio, P. G. Schultz, D. P. Millar, K. D. Janda, I. A. Wilson, H. Gray, R. A. Lerner: Deeply Inverted Electron-Hole Recombination in a Luminescent Antibody-Stilbene Complex Science, 319 (5867), 1232-5, (2008) PDF

24. J. Park, R. Jagasia, G. F. Kaufmann, J. C. Mathison, D. I. Ruiz, J. A. Moss, M. M. Meijler, R. J. Ulevitch, K. D. Janda: Infection control by antibody disruption of bacterial quorum sensing signaling. Chemistry & Biology , 14 (10), 1119-1127, (2007) PDF

23. S. De Lamo Marin, Y. Xu, M. M. Meijler, K. D. Janda: Antibody catalyzed hydrolysis of a quorum sensing signal found in Gram-negative bacteria. Bioorg. Med. Chem. Lett. 17 (6), 1549-52, (2007) PDF

22. V. V. Kravchenko, G. F. Kaufmann, J. C. Mathison, D. A. Scott, A. Z. Katz, M. R. Wood, A. B. Brogan, M. Lehmann, J. M. Mee, K. Iwata, Q. Pan, F. Fearns, U. G. Knaus, M. M. Meijler, K. D. Janda, R. J. Ulevitch: N-(3-oxo-acyl) homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways J. Biol. Chem. 281(39), 28822-30, (2006) PDF

21. E. P. Zorrilla, S. Iwasaki, J. A. Moss, J. Chang, J. Otsuji, K. Inoue, M. M. Meijler, K. D. Janda: Vaccination against weight gain Proc. Natl. Acad. Sci. USA 103(35), 13226-31, (2006) PDF

20. G. F. Kaufmann, R. Sartorio, S. H. Lee, J. M. Mee, L. J. Altobell 3rd, D. P. Kujawa, E. Jeffries, B. Clapham, M. M. Meijler, K. D. Janda: Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing J. Am. Chem. Soc. 128(9), 2802-3, (2006) PDF

19. H. Matsushita, N. Yamamoto, M. M. Meijler, P. Wirsching, R. A. Lerner, M. Matsushita, K. D. Janda: Chiral Sensing Using a Blue Fluorescent Antibody Mol. Biosystems 4, 303-6, (2005) PDF

18. M. Matsushita, M.M. Meijler, P. Wirsching, R. A. Lerner, K. D. Janda: A Blue Fluorescent Antibody-Cofactor Sensor for Mercury Org. Lett. 7(22), 4943-4946, (2005) PDF

17. K. M. McKenzie, M. M. Meijler, C. A. Lowery, G. E. Boldt, K. D. Janda: A Furanosyl-Carbonate Autoinducer in the Cell-to-Cell Communication System of V. harveyi Chem. Comm. 48, 4863-5, (2005) PDF

16. L. Qi, N. Yamamoto, M. M. Meijler, L. J. Altobell III, G. F. Koob, P. Wirsching, K. D. Janda: Δ-9-THC Immunochemical Studies: Haptens, Monoclonal Antibodies, and a Convenient Synthesis of Radiolabeled Δ-9-THC J. Med. Chem. 48(23), 7389-7399, (2005) PDF

15. C. A. Lowery, K. M. McKenzie, L. Qi, M. M. Meijler, K. D. Janda: Quorum Sensing in V. harveyi: Probing the Specificity of the LuxP Binding Site Bioorg. Med. Chem. Lett. 15(9), 2395-8, (2005) PDF

14. G. F. Kaufmann, M. M. Meijler, C. Sun, D.-W. Chen, J. M. Mee, D. P. Kujawa, T. Z. Hoffman, P. Wirsching, R. A. Lerner, K. D. Janda: Enzymatic Incorporation of Antibody-Inducible Fluorophores into DNA Angew. Chem. Int. Ed. Engl. 44(14), 2144-2148, (2005) PDF

13. M. M. Meijler, G. F. Kaufmann, L. Qi, J. M. Mee, A. R. Coyle, J. A. Moss, M. Matsushita, P. Wirsching, K. D. Janda: Synthesis and Properties of Fluorescent Cocaine Probes: Tools for the High-Throughput Selection of Cocaine Binding Antibodies J. Am. Chem. Soc. 127(8), 2477-84, (2005) PDF

12. G. F. Kaufmann, R. Sartorio, S.-H. Lee, C. Rogers, J. A. Moss, M. M. Meijler, B. Clapham, T. J. Dickerson, K. D. Janda: Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones Proc. Nat. Acad. Sci. USA 102 (2), 309-314, (2005) PDF

11. T. J. Dickerson, T. Lovell, M. M. Meijler, L. Noodleman, K. D. Janda: Mechanistic Studies of Nornicotine Catalyzed Aqueous Aldol Catalysis J. Org. Chem. 69 (20), 6603-6609, (2004) PDF

10. M. R. A. Carrera, M. M. Meijler, K. D. Janda: Cocaine Pharmacology and Current Pharmacotherapies for its Abuse Bioorg. Med. Chem. 12 (19), 5019-5030, (2004) PDF

9. M. R. A. Carrera, G. F. Kaufmann, J. M. Mee, M. M. Meijler, G. F. Koob, K. D. Janda: Treating Cocaine Addiction with Viruses Proc. Nat. Acad. Sci. USA 101 (28), 10416-10421, (2004) PDF

8. L. Qi, M. M. Meijler, S.-H. Lee, C. Sun, K. D. Janda: Solid-Phase Synthesis of Anandamide Analogues Org. Lett. 6 (10), 1673-1675, (2004) PDF

7. M. M. Meijler, G. F. Kaufmann, L. G. Hom, K. McKenzie, C. Sun, J. A. Moss, M. Matsushita, K. D. Janda: Synthesis and Biological Validation of a Ubiquitous Quorum Sensing Molecule Angew. Chem. Int. Ed. Engl. 43, 2106-2108, (2004) PDF

6. M. M. Meijler, M. Matsushita, P. Wirsching, K. D. Janda: Development of Immunopharmacotherapy Against Drugs of Abuse Curr. Drug Discovery Techn. 1 (1), 77-89, (2004)

5. J. A. Moss, A. R. Coyle, J.-M. Ahn, M. M. Meijler, J. Offer, K. D. Janda: Tandem IMAC-HPLC Purification of a Cocaine-Binding scFv Antibody J. Immunol. Methods. 281 (1-2), 143-148, (2003) PDF

4. M. M. Meijler, M. Matsushita, L. J. Altobell III, P. Wirsching, and K. D. Janda: A New Strategy for Improved Nicotine Vaccines using Conformationally Constrained Haptens J. Am. Chem. Soc. 125 (24), 7164-7165, (2003) PDF

3. M. M. Meijler, R. Arad Yellin, Z. I. Cabantchik and A. Shanzer: Synthesis and Evaluation of Iron Chelators with Masked Hydrophilic Moieties J. Am. Chem. Soc. 124 (43), 12666-12667, (2002) PDF

2. B. E. A. Burm, M. M. Meijler, J. Korver, M. J. Wanner and G. J. Koomen: Synthesis of the Brominated Marine Alkaloids Arborescidine A, B and C Tetrahedron 54 (22), 6135-6146, (1998) PDF

1. M. M. Meijler, O. Zelenko, D. S. Sigman: Chemical Mechanism of DNA Scission by (1,10 phenanthroline)copper. Carbonyl Oxygen of 5-Methylenefuranone is Derived from Water J. Am. Chem. Soc. 119 (5), 1135-1136, (1997) PDF

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