Dr. Ofer Yifrach: Publications 

1.         E. Magidovich, S. J. Fleishman and O. Yifrach (2006).

Intrinsically disordered C-terminal segments of voltage-activated potassium channels: a possible fishing rod-like mechanism for channel binding to scaffold proteins. Bioinformatics, 22, 1546-1550.

2.         E. Magidovich and O. Yifrach (2004).

Conserved gating hinge in ligand- and voltage-dependent K⁺ channels.

Biochemistry, 43, 13242-13247.

3.         S. J. Fleishman, O. Yifrach and N. Ben-Tal (2004).

Evolutionary conserved network of amino acids mediates gating in voltage-dependent potassium channels.

J. Mol. Biol. 340, 307-318.

4.         O. Yifrach (2004).

Hill coefficient for estimating the magnitude of cooperativity in gating transitions of voltage-dependent ion channels.

Biophys. J. 87, 822-830.

5.         O. Yifrach and R. MacKinnon (2002).

      Energetics of pore opening in a voltage-gated K⁺ channel.

      Cell, 111, 231-239.

6.         A. Horovitz, G. Kafri, Y. Fridman and O. Yifrach (2001).

      Allostery in Chaperonins.

      J. Struct. Biol. 135, 104-114.

7.         O. Yifrach and A. Horovitz (2000).

Coupling between protein folding and cooperative ATP binding in the GroEL chaperonin.

            Proc. Natl. Acad. Sci., U.S.A. , 97, 1521-1524.

8.         A. Horovitz and O. Yifrach (2000).

On the relationship between the Hill coefficients for steady-state and transient kinetic data: a criterion for concerted transitions in allosteric proteins.

            Bull. Math. Biol., 62, 241-246.

9.         A. Erbse, O. Yifrach, S. Jones and P. A. Lund (1999).

Chaperone activity of a GroEL protein that can exist in a single or double ring forms. J. Biol. Chem. 274, 20351-20357.

10.       O. Yifrach and A. Horovitz (1998).

Mapping the transition state of the allosteric pathway of GroEL by protein engineering.

            J. Am. Chem. Soc. 120, 13262-13263.

11.       O. Yifrach and A. Horovitz (1998).

Transient kinetic analysis of ATP binding-induced conformational changes in the allosteric chaperonin GroEL.

            Biochemistry  37, 7083-7088.

12.       H. E. White, S. Chen, A. M. Roseman, O. Yifrach, A. Horovitz and H. R. Saibil (1997).  Structural basis of allosteric changes in the GroEL mutant Arg197® Ala.

            Nat. Struct. Biol. 4, 690-694.

13.       O. Yifrach and A. Horovitz (1996).

            Allosteric control of non-folded protein binding to GroEL.

            J. Mol. Biol. 255, 356-361.        

14.       O. Yifrach and A. Horovitz (1995).

            Nested cooperativity in the ATPase activity of the oligomeric chaperonin GroEL.

            Biochemistry 34, 5303-5308.

15.       O. Kovalenko, O. Yifrach and A. Horovitz (1994).

            Residue Lys- 34 in GroES modulates allosteric transitions in GroEL.

            Biochemistry 33, 14974-14978.

16.       O. Yifrach and A. Horovitz (1994).

Two lines of allosteric communication in the oligomeric chaperonin GroEL are revealed by the single mutation Arg-196® Ala.

            J. Mol. Biol. 243, 397-401.

17.       A. Horovitz, E.S. Bochkareva, O. Yifrach and A.S. Girshovich (1994).

Prediction of an inter-residue interaction in the chaperonin GroEL from multiple sequence alignment is confirmed by double mutant cycle analysis.

            J. Mol. Biol. 233, 133-138.